Categoria: Artigos
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29 ago 2025
>> Phase 3 Trial of Inhaled Molgramostim in Autoimmune Pulmonary Alveolar Proteinosis
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Título do Estudo Phase 3 Trial of Inhaled Molgramostim in Autoimmune Pulmonary Alveolar Proteinosis Fonte Trapnell BC, Inoue Y, Bonella F, Wang T, McCarthy C, Arai T, Akasaka K, Mariani F, Mogulkoc N, Song JW, Baba T, Jouneau S, Numakura T, Öcal N, Mihaltan F, Ataya A, Bendstrup E, Campo I, Carey B, Arena R, […]
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22 ago 2025
>> Sotatercept in Patients with Pulmonary Arterial Hypertensionat High Risk for Death
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Título do Estudo Sotatercept in Patients with Pulmonary Arterial Hypertensionat High Risk for Death Fonte Marc Humbert, Vallerie V. McLaughlin, David B. Badesch, H. Ardeschir G., J. Simon R. Gibbs, Mardi Gomberg-Maitland, Ioana R. Preston, Rogerio Souza, Aaron B.Waxman, et al. The New England Journal of Medicine May 29, 2025; 392:1987-2000. https://doi.org/10.1056/NEJMoa2415160 Introdução Hipertensão […]
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16 ago 2025
>> Correlations between exercise oxygen consumption, lung function, image findings, and quality of life in adults with post-tuberculosis lung disease
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Título do Estudo Correlations between exercise oxygen consumption, lung function, image findings, and quality of life in adults with post-tuberculosis lung disease Fonte Chron Respir Dis. 2025 22:14799731251345492. doi: 10.1177/14799731251345492. PMID: 40404177; PMCID: PMC12099090. da Silva MPVL, da Silva Pinto PVL, Fonseca IMPP, de Lima LS, Carneiro AS, Costa W, Santos AP, Lopes AJ. Chron […]
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8 ago 2025
>> A Multidimensional Diagnostic Approach for Chronic Obstructive Pulmonary Disease
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Título do Estudo A Multidimensional Diagnostic Approach for Chronic Obstructive Pulmonary Disease Fonte JAMA. doi:10.1001/jama.2025.7358 Introdução O diagnóstico tradicional da Doença Pulmonar Obstrutiva Crônica (DPOC) baseia-se na presença de obstrução ao fluxo aéreo na espirometria após broncodilatação (VEF1/CVF após BD < 0,70) em pacientes persistentemente sintomáticos e com fatores de etiológicos compatíveis. No entanto, […]
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27 jul 2025
>> Obstructive Sleep Apnea in Patients with Fibrotic Interstitial Lung Disease (Nonidiopathic Pulmonary Fibrosis): What Should be Offered?
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Título do Estudo Obstructive Sleep Apnea in Patients with Fibrotic Interstitial Lung Disease (Nonidiopathic Pulmonary Fibrosis): What Should be Offered? Fonte Cardoso CG, Valente C, Serino M, Rodrigues I, Carvalho A, Coelho DB, Bastos HN, Mota PC, Morais A, Drummond M. Obstructive sleep apnea in patients with fibrotic interstitial lung disease (non-idiopathic pulmonary fibrosis): what […]
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11 jul 2025
>> Nerandomilast in Patients with Idiopathic Pulmonary Fibrosis
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Título do Estudo Nerandomilast in Patients with Idiopathic Pulmonary Fibrosis Fonte N Engl J Med 2025;392:2193-202. DOI: 10.1056/NEJMoa2414108 Introdução A fibrose pulmonar idiopática (FPI) é uma doença pulmonar intersticial fibrosante caracterizada pelo declínio progressivo da função pulmonar. Medicamentos antifibróticos, nintedanibe e pirfenidona, desaceleram o declínio da função pulmonar em pacientes com FPI. No […]
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6 jul 2025
>> Enhancing diagnostic precision: a multicentric study of endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy in lymphoproliferative disorders
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Título do Estudo Enhancing diagnostic precision: a multicentric study of endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy in lymphoproliferative disorders Autores Ariza-Prota M, Pérez-Pallarés J, Barisione E, et al. Enhancing diagnostic precision: a multicentric study of endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy in lymphoproliferative disorders. ERJ Open Res 2025; in press (https://doi.org/10.1183/23120541.00775-2024). Fonte European Respiratory Journal […]
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27 jun 2025
>> Peak Inspiratory Flow and Inhaler Prescription Strategies in a Specialized COPD Clinical Program – A Real-World Observational Study
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Título do Estudo Peak Inspiratory Flow and Inhaler Prescription Strategies in a Specialized COPD Clinical Program – A Real-World Observational Study Pico de Fluxo Inspiratório e Estratégias de Prescrição do Inalador em um Serviço Especializado em DPOC- Um Estudo Observacional do Mundo Real Autores Sarah Pankovitch, MD; Michael Frohlich, MD; Bader AlOthman, MD; Jeffrey […]
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14 jun 2025
>> Barriers to Clinical Remission in Severe Asthma
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Título do Estudo Barriers to Clinical Remission in Severe Asthma Fonte FARINHA I., HEANEY L.G. Barriers to clinical remission in severe asthma [online]. 2024, Respiratory Research 25:178. Disponível em https://respiratory-research.biomedcentral.com/articles/10.1186/s12931-024-02812-3 . Acesso em abril 2025. Introdução Os autores iniciam o texto com uma revisão conceitual sobre a asma, pretendendo dirigir o foco do trabalho para […]
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6 jun 2025
>> Dupilumab for chronic obstructive pulmonary disease withtype 2 inflammation: a pooled analysis of two phase 3, randomised, double-blind, placebo-controlled trials
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Título do Estudo Dupilumab for chronic obstructive pulmonary disease withtype 2 inflammation: a pooled analysis of two phase 3, randomised, double-blind, placebo-controlled trials Fonte BHATT, Surya P. et al. Dupilumab for chronic obstructive pulmonary disease with type 2 inflammation: a pooled analysis of two phase 3, randomised, double-blind, placebo-controlled trials. Lancet Respiratory Medicine, v. 13, […]
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